Abstract
Glycosphingolipids (GSL) are implicated to play an important role in insulin resistance. We have recently described (using several rodent models of type 2 diabetes) that lowering of GSL synthesis by pharmacological inhibition of glucosylceramide synthase with the iminosugar AMPDNM, improves insulin sensitivity in adipocytes, liver and muscle.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
