Abstract
It is likely that hypoglycaemia unawareness (HU) is in part determined by genetic factors. In a small cohort, we found that a single nucleotide polymorphsim (SNP) of the gene encoding the β2-adrenergic receptor (ADRB2) was associated with HU in patients with type 1 diabetes (T1D). Genes that have been associated with the incidence of severe hypoglycaemia in patients with T1D are plausible candidates for an association with HU. The aim of this study was to investigate various candidate genes for associations with HU in a contemporary T1D patient cohort.
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