PS1-01 Nitric oxide modulation by retinoic acid, IL-17A and TNF-α in PBMC and colonic mucosa cultures from Algerian patients with inflammatory bowel disease

Abstract

This article presents a method of conducting a scoping review that synthesizes recommendations from previous literature while contributing additional customizations to enhance a team-based, mixed method approach. A form of knowledge synthesis, scoping reviews aim to describe the breadth of an existent knowledge base and inform future research, practice, and policy. Scoping review methodology has continued to evolve since the inception of the Arksey and O’Malley Framework in 2005. After examining recommendations from the body of literature on scoping review methodology and scoping reviews about scoping reviews, we found that teamwork and mixed method approaches were rarely addressed. Following the Arksey and O’Malley Framework, we discuss current recommendations within the literature, rationale for our customizations to enhance the method, and present an application of these customizations as illustrated in our companion article, “Outcomes and outputs affiliated with children’s advocacy centers in the United States: A scoping review.”In sum, our enhancements to the Arksey and O’Malley Framework:•Explicitly integrate qualitative and quantitative assessment of the literature following best practices in mixed methods research, and,•Integrate a team-based approach throughout all stages of the scoping review process.