PS-07-001 20-year follow-up after penile prosthesis implantation: Functional and quality of life outcomes

Abstract

Assess the long-term complications, functional and quality of life (QoL) outcomes following 3-piece inflatable penile prosthesis implantation (IPP). Data of 65 consecutive patients submitted to IPP between 1991 and 2001 at a single center were analyzed. Baseline and perioperative data were analyzed. Patients were regularly reassessed over the follow-up (FU) to evaluate rate of complications and functional outcomes. The validated questionnaire Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) was used to assess patients’ QoL. Kaplan Meier analysis estimated the probability of prosthesis survival (defined as working device/not-explanted). Cox regression analysis assessed predictors of IPP failure. Median (IQR) FU was 206 months (145, 257). Of all, 14(9.4%) patients were dead at FU assessment and functional data could not be retrieved. Etiology of erectile dysfunction (ED) was vasculogenic (N=20; 39%), Peyronie disease (N=15; 29%), pelvic surgery (N=4; 7.8%), organic other than vasculogenic (N=3; 5.9%) and others (N=9; 18%). Of 51, 42 (83%) and 9 (17%) patients were implanted with either a peno-scrotal and a suprapubic approach, respectively. Throughout the FU, 24 (49%) patients experienced complications [mechanical failure (79%); pain (12%); orgasmic dysfunctions (4.2%); device infection (4.2%)]. The estimated IPP survival was 53% (95%CI:36-67) at 240-mos FU. Patients baseline characteristics (age; CCI; BMI; ED etiology) were not predictors of IPP failure over time. At 240-mos FU, 41% (95%CI 19-49) still used the device. Among them, QoLSPP median (IQR) domain scores were high: functional 22/25 (20, 23), relational 17/20 (15, 18), personal 14 (12, 15), social 14/15 (11, 15).