PS01.119: TO INVESTIGATE WHETHER BILATERAL MEDIASTINAL PLEURA SHOULD BE REMOVED IN I-IIA ESOPHAGEAL CANCER SURGERY

Abstract

Abstract Background For thoracic segment esophageal range, Some think resect double side mediastinal pleura. other think never resection has no difference, increased complications. Methods This study used a prospective, randomized controlled study method. 213 patients with I-IIIA esophageal cancer were randomly divided into two groups. one group of 106 patients were completely removed with bilateral mediastinal pleura. Another group of 107 patients had the mediastinal pleura in the implementation; Both groups performed a thoracic lymph node dissection. we observed the incidence of pleural effusion, pulmonary infection rate, chest infection rate, OS, thoracic metastatic tumor incidence, and the postoperative review PET- CT. Results Among the 106 patients, there were 11 cases of pleural metastasis, 8 cases of chest infection and 33 cases of pulmonary infection, thoracic drainage tube pulling time averaged 3.8 days. After surgery three months, six months, one year, two years, 47 cases PET-CT are positive. an average 5-year survival rate of 47.3%. In other group, 15 patients with pleural metastases, 5 patients with chest infection, 19 in the lungs, thoracic drainage tube pulling time averaged 3.4 days. After surgery three months, six months, one year, two years, 43 cases PET-CT are positive and an average 5-year survival rate of 46,8%.. Conclusion This study is a prospective study on mediastinal pleural resection of esophageal cancer. Experimental conclusion found two groups of patients with pleural and pleural metastasis rate was not significant difference, and the chest cavity infection and pulmonary infection rate, less resection in patients with bilateral mediastinal pleura resection group is more, chest tube pull out two groups of almost the same time, there was no significant difference. Postoperative three months, six months, one year, two years PET-CT results, no significant difference in chest positive results. Patients with bilateral mediastinal pleural resection had a higher chest discomfort. In conclusion, it was concluded that there was no significant advantage in the surgical excision of bilateral mediastinal pleura in patients with esophageal cancer, and there were many complications. The sample size of this experiment is small, which is a single center study, and more large samples are needed. Disclosure All authors have declared no conflicts of interest.