PS-C11-4: UPPER ARM SBP DECLINE ASSOCIATED WITH REPEATED CUFF-OSCILLOMETRIC INFLATION SIGNIFICANTLY CORRELATED WITH ARTERIAL STIFFNESS INDEX

Abstract

Background: It is unknown how the repeated cuff-oscillometric inflations with blood pressure measurements are related to arterial stiffness and central arterial pressure, and how changes to the novel indexes of arterial stiffness, AVI (arterial velocity pulse index) and API (arterial pressure volume index) will be brought about by the repeated cuff-oscillometric inflations. Aim: We evaluated the clinical significance of the new non-invasive vascular indexes AVI and API in outpatients with various clinical backgrounds to explore potential utilities of these two indexes by using repeated cuff-oscillometric inflation in actual clinical settings. Methods: In 250 consecutive outpatients, we performed a cross-sectional, retrospective, single center, observational study to investigate arterial stiffness using blood pressure and the AVI and API with three times repeated measurements that used multifunctional blood pressure monitoring device, AVE-1500 (Shisei Datum, Tokyo, Japan). Results: Of the 250 enrolled subjects, 236 were analyzed. 62.7% of the patients were male, with an overall mean age of 68.1 ± 12.1. The mean SBP (systolic blood pressure) and DBP (diastolic blood pressure) of first time measurement were 133.07 ± 21.20 mmHg and 73.94 ± 13.56 mmHg, respectively. The mean AVI and API of first time measurement were 23.83 ± 8.30 and 31.12 ± 7.86, respectively. In each measurement with repeated measurements of BP (SBP/DBP), AVI and API, although DBP and AVI did not have the significant changes throughout the measurements, both SBP and API decreased significantly according to the measurement orders. Conclusions: In this study, upper arm SBP decline associated with repeated cuff-oscillometric inflation significantly correlated with arterial stiffness index. Furthermore, it would suggest that arterial stiffness could be predicted by the changes in repeated SBP measurements.