PS-BPP05-6: THE ASSOCIATION BETWEEN SLEEP AND BLOOD PRESSURE CONTROL AMONG THE COMMUNITY DWELLING OLDER ADULTS TAKING ANTIHYPERTENSIVE DRUGS: THE SONIC STUDY

Abstract

Purpose: Short sleep duration and poor sleep quality in middle age have been reported to affect blood pressure(BP) control. However, the association between sleep duration, sleep quality and BP control is controversial in older adults with hypertension taking antihypertensive drugs. The aim of this study was to investigate this association in 70–80-year-old participants in the Japanese study of Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC). Method: Of the participants in the SONIC study, we performed a cross-sectional analysis of participants with hypertension taking antihypertensive drugs aged 76 ± 1 (n = 242) and 86 ± 1 (n = 196) years who had cooperated in the sleep survey. Sleep duration and quality were evaluated by the Pittsburgh Sleep Quality Index(PSQI). The subjects were categorized as < 6(short) and > = 6 hours. A PSQI> = 6 defined poor sleepers and a PSQI< = 5 defined good sleepers. BP control was defined as average systolic BP < 140mmHg and diastolic BP < 90mmHg as controlled status. We performed the multivariable logistic regression to investigate the association between sleep duration, sleep quality and BP control adjusted for the following confounding factors: age, sex, body mass index, frail, smoking, alcohol consumption, medical history, depressive symptoms separately for each age group. Results: In the age 70 years, logistic regression analysis indicated that neither sleep duration nor sleep quality association BP control. On the other hand, in the age 80 years, sleep duration of < 6 hours was associated with poor BP control(OR = 4.87, 95% CI: 1.54–15.41,P = 0.007) when compared to sleep duration of > = 6 hours and sleep quality was not significantly associated with BP control. Conclusion: In the age 80 years, sleep duration of < 6 hour was associated with poor BP control. These results indicate that adequate sleep may be important for BP control in older adult, especially age around 80 years.