PS-BPC06-2: CLINICAL CHARACTERISTICS OF COMORBID HYPERTENSION AND CORONARY ARTERY DISEASE IN 10 YEARS: RESULTS FROM CHINA

Abstract

Background: Little is known regarding the clinical profiles of patients with comorbid hypertension and coronary artery disease (HT-CAD) in China. Methods: The current study was conducted in a large-scale tertiary hospital that gathered nationwide patients of China. A total of 32,355 CAD patients with and without hypertension admitted from 5 August 2008 to 22 July 2018 were identified in this cross-sectional study. The demographic characteristics, diagnosis records, relevant examinations, treatment patterns, and in-hospital outcomes of patients were abstracted via electronic medical record database. We analyzed the overall comorbidity rate, blood pressure control, clinical characteristics and their temporal change of patients with HT-CAD in the current study. Results: The overall comorbidity rate of hypertension in patients with CAD was 64.12% (N = 20,747) and did not significantly change during 2008 to 2018. Female CAD patients and CAD patients in east coastal regions had significantly higher comorbidity rate of hypertension. Among patients with HT-CAD, the BP was controlled at < 140/90 mmHg in 52.39% and < 130/80 mmHg in 27.03%. The control rate of < 130/80 mmHg increased during 2008 to 2018, whereas the control rate of < 140/90 mmHg did not change significantly. Compared with the counterparts with nonHT-CAD, patients with HT-CAD had higher incidence of cardiovascular-related comorbidities, and most of these comorbidities showed an increasing trend over the study period. Conclusions: Hypertension is the most prevalent comorbidity in Chinese patients with CAD. Patients with HT-CAD have an increasing health burden and should be paid with special attention to improve their cardiovascular outcomes.