PS-173 Keeping Ahead Of The Curve: What Is The Relationship Between Lung Function And Severity Of Scoliosis?

Abstract

<h3>Background</h3> Scoliosis is a common condition that affects lung function, causing a restrictive pattern of abnormality. The effect on lung function is important as outcomes from corrective surgery are influenced by Forced Vital Capacity (FVC) and Forced Expiratory Volume (FEV₁). The relationship between FVC, FEV₁ and degree of scoliosis is poorly described. We undertook a retrospective study comparing the radiographic measures of spinal curvature (Cobb angles and apex) with clinical lung function testing (% predicted FEV₁/FVC). We have data on over 300 children (&lt;18 yrs) with scoliosis who have had lung function testing. These preliminary results are from a cohort of 62 children. <h3>Aims</h3> To investigate the correlation between the severity of the thoracic curve and lung function. Secondary outcomes included comparing the position of the curve apex and Cobb angle with lung function. <h3>Methods</h3> Spinal X-ray images were analysed to look at Cobb angle, thoracic curvature, and apex of the curve. FVC and FEV₁ were measured in our lung function lab and presented as percent predicted. Data analysis was done using SPSS. <h3>Results</h3> Both an increase in thoracic curvature and Cobb angle are associated with worsening FEV₁/FVC (p = 0.06/0.02 and 0.004/0.006 respectively). The comparison with Apex showed no statistical significance (p = 0.405/0.337). <h3>Conclusion</h3> Increasing spinal curvature is significantly correlated with worsening lung function. Surprisingly, the maximal curve (Cobb angle) appears a better predictor of FVC than thoracic curve.