PS-08-008 Clinical characteristics of men complaining of premature ejaculation together with erectile dysfunction: A cross-sectional study

Abstract

Premature ejaculation (PE) is present in up to 30% of men with erectile dysfunction (ED). To assess the clinical features of men complaining of both ED and PE (ED-PE) as compared to men reporting only ED or PE. A consecutive series of 4024 men (mean age 51.2±13.2 years) consulting for sexual dysfunction was studied. The population was categorized into ED-only (n=2767;68.8%), PE-only (n=475;1.8%) and ED-PE (n=782;19.4%). Sexual symptoms were evaluated using the structured interviews SIEDY and ANDROTEST. Penile color Doppler ultrasound (PDCU) parameters were also assessed. When compared to PE alone, ED-PE reported more sexual complaints, including impaired morning erections (OR=5.8[4.1;8.3]), decreased sexual desire (OR=2.6[1.8;3.7]), decreased ejaculate volume (OR=2.7[1.8;4.0]) and reduced frequency of sexual intercourse (OR=1.4[1.0;2.0]). Conversely, ED-PE and ED-only men had a similar prevalence of sexual symptoms. In ED-PE men, the characteristics of ED were similar to ED-only men, whereas the characteristics of PE were milder than in PE-only men. ED-PE men had a significantly higher prevalence of hypertension, diabetes and cardiovascular (CV) diseases (OR=1.8[1.1;3.0], 2.7[1.3;5.6] and 2.7[1.1;6.5], respectively) than PE-only subjects. Moreover, ED-PE men showed worse dynamic peak systolic velocity at PDCU (B= -12.0[-17.7;-6.2]) and a greater 10-year estimated CV risk (B=3.8 [2.5;5.1]) than PE-only patients. Conversely, comorbidities and PDCU parameters were similar in ED-PE and ED-only men.