Abstract
Pruritic papular eruption of HIV: a review article
Highlights
Itching is a common complaint among human immunodeficiency virus (HIV) patients and may cause significant morbidity and embarrassment
Pruritic papular eruption associated with Human Immunodeficiency Virus infection (PPE-HIV), was described by James et al in 1985 as a chronic pruritic papular dermatitis seen in patient suffering from Acquired Immunodeficiency Syndrome (AIDS) [3]
In 2012, Afonso et al [33] studied the association between pruritic papular eruption and eosinophilic folliculitis and HIV infection in Brazil, and postulated that eosinophilic folliculitis is characterized by a folliculocentric collection of eosinophils with some overlap of these features with papular eruptions (PPE) and suggested that the two condition could be part of the same disease spectrum
Summary
Itching is a common complaint among HIV patients and may cause significant morbidity and embarrassment. Pruritic papular eruption associated with Human Immunodeficiency Virus infection (PPE-HIV), was described by James et al in 1985 as a chronic pruritic papular dermatitis seen in patient suffering from Acquired Immunodeficiency Syndrome (AIDS) [3]. This skin condition remains the most common cutaneous manifestation in the HIV-infected patient and it is more prevalent in developing countries [4,5,6,7,8,9,10]. PPE-HIV is regarded as WHO clinical stage II for infants and children [12] in adults, PPE manifest in advanced immunosuppressive stage with low CD4 count in majority of cases, but they may appear as an initial cutaneous disease with high CD4 count [13]
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