Abstract
BACKGROUND AND AIM: In 2016 indoor pollution caused 3.8 million deaths attributable to respiratory, cardiovascular diseases and cancers. The aim of this study is to evaluate in our Marche region, possible association between hospitalization for asthma, Extrinsic Allergic Alveolitis (EAA) and Carbon Monoxide Intoxication (COI) and two proxy indicators of the exposure to indoor air pollution, such as PM2.5 concentration and socioeconomic deprivation index (DI). METHODS: We included subject’s hospital admissions residing in the Marche region between 2006 and 2013. For PM2.5 air concentrations we used estimates provided by the atmospheric modelling system of Italian National Integrated Assessment Model (AMS-MINNI). Exposure was defined on the basis of the quintiles of PM2.5 municipalities distribution values. Socio-economic disadvantage was measured through the DI built considering five features of the resident population: low instruction, unemployment/first job-employment, rent living, being part of a single parent family and high population density. The DI provides following municipalities classification: very wealthy, wealthy, middle, deprived, very deprived. RESULTS:Regarding asthma, results show a higher risk of hospitalization with the increasing of PM2.5 concentration quintiles. The risk increases by 35% (90% CI 1.09-1.65) for the third and fourth quintile compared to the first and 30% (90% CI 1.07-1.59) for the highest quintile. For EAA and CO intoxication there is an evident risk gradient of hospitalization as the DI increases despite the low number of events for these pathologies. CONCLUSIONS:This work confirms that PM2.5 concentration has an impact in increasing hospital admissions due to asthma and suggests a possible correlation between lower socio-economic status and increased risk of hospitalization due to EAA and CO intoxication. KEYWORDS: Air pollution, Socio-economic factors, Allergies, Respiratory outcomes, Asthma
Published Version
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