Abstract
Abstract A patient presented with spinal cord compression due to extramedullary hematopoiesis. She was treated with decompressive surgery followed by proton beam radiation therapy to a dose of 2340 cGy relative biological effectiveness in 13 fractions. After 6 months of follow-up she has had a near complete recovery from her initial symptoms and remains free from extramedullary hematopoiesis around the spinal cord. Proton beam radiation therapy was chosen over conventional linear accelerator-based radiation therapy due to the normal-tissue sparing effects and potential decreased risk of secondary neoplasia. Proton beam radiation therapy should be considered for cases of spinal cord compression from extramedullary hematopoiesis involving young patients at risk for long-term complications.
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