Proton chemical shift anisotropy measurements of hydrogen-bonded functional groups by fast magic-angle spinning solid-state NMR spectroscopy

Luminita Duma,Geoffrey Bodenhausen,Daniel Abergel,Piotr Tekely

doi:10.1039/b801154k

Abstract

The suitability of fast MAS solid-state NMR spectroscopy for probing (1)H chemical shift anisotropy of hydrogen-bonded species has been demonstrated.

Highlights

Hydrogen bonds play a central role in determining molecular conformation and aggregation in areas ranging from inorganic to biological chemistry.[1,2] The description and understanding of the nature of intermolecular contacts in hydrogen-bonded systems remains a challenging problem
The suitability of fast magic-angle spinning (MAS) solid-state Nuclear Magnetic Resonance (NMR) spectroscopy for probing 1H chemical shift anisotropy of hydrogen-bonded species has been demonstrated
Proton NMR spectroscopy has long been used to investigate the nature of hydrogen-bonded systems.[3]

Summary

Introduction

Hydrogen bonds play a central role in determining molecular conformation and aggregation in areas ranging from inorganic to biological chemistry.[1,2] The description and understanding of the nature of intermolecular contacts in hydrogen-bonded systems remains a challenging problem. Proton chemical shift anisotropy measurements of hydrogen-bonded functional groups by fast magic-angle spinning solid-state NMR spectroscopyw

Results

Conclusion