Abstract

In order to demonstrate the feasibility of the proton microprobe in the analysis of dermatological material when a spatial resolution of a few micrometres is sufficient and to compare it with the electron microprobe technique, duplicate sections of human skin have been analysed with both methods. A skin sample was obtained from each of three healthy volunteers. After cryosectioning (12 μm) and freeze-drying adjacent sections of each sample were scanned by the electron microprobe and the proton microprobe, respectively.

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