Abstract

ObjectiveTo demonstrate the feasibility of cardiac magnetic resonance (CMR) cine sequences with compressed-sensing (CS) acceleration in the assessment of ventricular anatomy, volume, and function; and to present a fast CRM protocol that improves scan efficiency. MethodsProspective study of consecutive patients with indication for CMR who underwent CS short-axis (SA) cine imaging compared with conventional SA cine imaging. We analysed ejection fraction (EF), end-diastolic volume (EDV), stroke volume (SV), and myocardial thickness. Two blinded independent observers performed the reading. Inter- and intraobserver agreement was calculated for all the measurements. Image quality of conventional and CS cine sequences was also assessed. ResultsA total of 50 patients were included, 22 women (44%) with a mean age of 57.3±13.2 years. Mean left ventricular EF was 59.1%±10.4% with the reference steady-state free precession sequences, versus 58.7%±10.6% with CS; and right ventricular EF with conventional imaging was 59.3%±5.7%, versus 59.5%±6.1% with CS. Mean left ventricular EDV for conventional sequences and CS were 166.8 and 165.1ml respectively; left ventricular SV was 94.5 versus 92.6ml; right ventricular EDV was 159.3 versus 156.4 ml; and right ventricular SV was 93.6 versus 91.2ml, respectively. Excellent intra and interobserver correlations were obtained for all parameters (Intraclass correlation coefficient between 0.932 and 0.99; CI: 95%). There were also no significant differences in ventricular thickness (12.9±2.9mm vs. 12.7±3.1mm) (p<.001). The mean time of CS SA was <40 sec versus 6-8 min for the conventional SA. The mean duration of the complete study was 15±3 min. ConclusionsCine CS sequences are feasible for assessing biventricular function, volume, and anatomy, enabling fast CMR protocols.

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