Abstract

Pulmonary thromboembolism (PTE) is a condition characterized by a wide range of clinical manifestations with different prognosis and treatment. In absence of any specific diagnostic test, diagnosis of acute and symptomatic PTE relies on clinical suspicion, D-dimer results and imaging tests. Approved diagnostic algorithms improve the prognosis in patients suspected of PTE. Early treatment goals are to stabilize the patient, to improve symptoms, to restore vascular permeability and to prevent relapses. In most cases, those goals are achieved by the use of conventional anticoagulation therapy, which avoids thrombus progression. On the other hand, endogenous fibrinolytic system resolves vascular obstruction and develops collateral circulation. Anticoagulant therapy has to be stablished quickly regardless diagnostic process. Hemodynamic status at the time of diagnosis is the most important prognostic factor in PTE.

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