Abstract

A proteinuria greater than 150mg/day should be studied. Glomerular proteinuria is due to a damage in the glomerular filtration barrier. The finding of proteinuria in patients with negative urinary dipstick should suggest tubular proteinuria or overload proteinuria. Once discarded transient and orthostatic proteinuria is necessary to quantify proteinuria by its measurement in 24 hour urine. Nephrotic syndrome is characterized by a 24-hour proteinuria>3.5g accompanied by hypoalbuminemia, edema, hyperlipidemia and lipiduria. To determine the precise cause of proteinuria and its appropriate treatment, it is necessary a complete patient evaluation, including history and physical examination, as well as urinalysis and other laboratory tests. The performance of a renal biopsy is necessary in some patients.

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