Protocolo diagnóstico de la leucocitosis con formas celulares anómalas

Abstract

IntroductionIt is important to evaluate the leukocytosis in relation to the absolute range of different types of white blood cells, also assessing the presence of abnormal cellular forms. Therefore, detection of leukocytosis requires a quick scrutiny of automated differential formula and other parameters of blood count, and the study of smear conducting a manual recount of blood leukocyte formula. NeutrophiliaIn neutrofilias with anomalous forms we can find myelemia or left shift (infections or chronic myeloid leukemia) or a leukoerythroblastic syndrome (myelofibrosis or solid tumor infiltration). LymphocytosisIf what prevails is a lymphocytosis with atypical forms, the most important diagnostic groups are mononucleósicos syndromes and lymphoid neoplasms (B or T), both precursor cells and mature lymphocytes. MonocytosisOn the contrary, we must rule out the presence of immature cells in peripheral blood before monocitosis and leukocytosis associated with cytopenias (acute myeloid leukemia or chronic myelomonocytic leukemia).