Abstract
When faced with a finding of hypertransaminasemia on a blood test in patients who consult at the emergency department, it is essential to try to discern its acute or chronic nature as well as the presence or absence of gastrointestinal or systemic symptoms that may be related. Likewise, transaminases lack a high degree of sensitivity and specificity for diagnosing the causative disease. However, they can point to a cytolytic (hepatocellular) or a cholestatic (bile duct obstruction) origin. For this reason, personal, epidemiological, clinical, analytical, radiological, and anatomic pathological data must be known in order to make a differential diagnosis in each case. This protocol aims to review and clarify the diagnostic approach to hypertransaminasemia in the field of emergency department medicine.
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