Abstract
Background: Given the high incidence of falls and their associated negative effects, the development of effective falls prevention interventions for people with Multiple Sclerosis (MS), Parkinson's Disease (PD) and stroke is a priority. Currently the implementation of condition-specific falls prevention interventions is challenging in the community due to lack of participants and resources. Given the similarities in falls risk factors across stroke, PD and MS, the design of mixed-diagnosis interventions for groups comprising of people with these three neurological conditions may solve these implementation challenges. Having a core outcome set (COS) for evaluating these interventions would enable the comparison and combination of data, thereby facilitating progress in this research area. Therefore, the aim of this research study is to develop a COS for evaluating mixed-diagnosis falls prevention interventions for people with MS, PD and stroke. Methods: This will be a mixed-methods, international, multi-perspective Delphi consensus study with five stages. Stage one will involve the identification of potential outcomes through a systematic literature search, patient focus groups, and consultation with our Public and Patient Involvement (PPI) panel. The second stage will be the development of the Delphi survey using the outcomes elicited from stage one. Stage three will be the prioritisation of outcomes using a two-round online Delphi survey involving patients, clinicians, researchers and policy-makers/service-planners. The fourth stage will be to identify and recommend outcome measures and definitions. The final stage will be a consensus meeting with representatives from each stakeholder group to agree upon the final COS. Discussion: Adoption of this COS in future trials investigating the effectiveness of mixed-diagnosis falls prevention interventions for people with MS, PD and stroke will facilitate the comparison and combination of research findings. This should translate into improved decision-making by service-planners/policy-makers and clinicians regarding the implementation of evidence-based falls prevention interventions into practice.
Highlights
Neurological conditions are the main cause of disability globally and, people with neurological conditions have high rehabilitation needs[1,2]
The final stage will be a consensus meeting with representatives from each stakeholder group to agree upon the final core outcome set (COS). Adoption of this COS in future trials investigating the effectiveness of mixed-diagnosis falls prevention interventions for people with Multiple Sclerosis (MS), Parkinson's Disease (PD) and stroke will facilitate the comparison and combination of research findings
This should translate into improved decision-making by service-planners/policy-makers and clinicians regarding the implementation of evidence-based falls prevention interventions into practice
Summary
Neurological conditions are the main cause of disability globally and, people with neurological conditions have high rehabilitation needs[1,2]. In Ireland, three common neurological conditions with high falls rates are Multiple Sclerosis (MS), Parkinson’s Disease (PD) and stroke and, there is a need to develop effective falls prevention interventions to facilitate evidence-based service planning and resource allocation[3]. As a result of the high incidence of falls and the associated negative consequences, falls prevention for people with MS, PD and stroke is an important topic for research and the provision of healthcare services. Given the high incidence of falls and their associated negative effects, the development of effective falls prevention interventions for people with Multiple Sclerosis (MS), Parkinson's Disease (PD) and stroke is a priority. Given the similarities in falls risk factors across stroke, PD and MS, the design of mixed-diagnosis interventions for groups comprising of people with these three neurological conditions may solve these implementation challenges. The aim of this research study is to develop a COS for evaluating mixeddiagnosis falls prevention interventions for people with MS, PD and stroke.
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