Protocol for a scoping review of fecal microbiota transplantation from patients into animals

Abstract

Microbiota studies have uncovered numerous associations between human gut microbes and health-related outcomes. However, since most of these correlations were observed in cross-sectional studies, the causal inference is limited. The causal contribution of microbiota can be evidenced through disease induction or exacerbation in animal models after fecal microbiota transplantation (FMT) from patients.