Abstract
Polymer-based phosphopeptide or glycopeptide enrichment materials are reviewed by Taolei Sun and co-workers in article number 1604670. In addition to high grafting densities and abundant binding sites, smart polymers display a dramatic conformational transition from globule to coil upon complexation with target peptides, enabling highly controllable binding/release behaviors of the peptides on material surfaces, which opens up a unique approach toward resolving the enrichment problems in post-translational modification proteomics.
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