Abstract
Using a genetically defined human ovarian cancer model, we have analyzed the protein expression profile of human ovarian cancer cells established by oncogenic RAS transformation. Cells were immortalized by retroviral transfection of SV40 t/T antigens and the catalytic subunit of telomerase (hTERT). Careful analyses of protein targets associated with oncogenic transformation have enabled us to identify several novel signaling pathways that play important roles in oncogenic transformation of human ovarian epithelial cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
