Abstract

The origin of incompetent cervix is multifactorial, and the success of RC unpredictable. Intra-amniotic inflammation complicates 25% of pregnancies undergoing RC, and its presence predicts failure. An intra-amniotic proteomic inflammatory profile was described by SELDI (mass restricted: MR Score). We report here a new independent biomarker predictive of cerclage failure whose impact is synergistic with a+MR.

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