Abstract
The weight of the liver is one of the important selection criteria in the quality of “foie gras”. This factor is highly variable despite the fact that individuals are reared, overfed and slaughtered in the same way. In this study, we performed an analysis of the proteome profile of two weight classes of light (between 550 and 599 g) and heavy (more than 700 g) livers. For the analysis of the proteic extracts, a liquid chromatographic analysis coupled with mass spectrometry was carried out. In low-weight livers, aerobic energy metabolism, protein metabolism and lipid metabolism oriented toward export and beta-oxidation were overexpressed. On the contrary, high weight livers were characterized by anaerobic energy metabolism and a more active protein catabolism associated with cell apoptosis and reorganization of the cell structure.
Highlights
The production of “foie gras” is a tradition that has crossed the ages since the ancient Egyptians
Proteins play a key role in the metabolism of the liver during the development of the fatty liver induced by overfeeding they represent less than 8% of the total fresh matter (Théron, 2011; Bax et al, 2012) at the end of the overfeeding period
A Partial Least SquaresDiscriminant Analysis (PLS-DA) between the two studied groups was performed on significant proteins
Summary
The production of “foie gras” is a tradition that has crossed the ages since the ancient Egyptians. To obtain this product, palmipeds are overfed twice a day for a minimum period of 10 days with a hypercaloric diet, based on corn supplemented or not with a commercial premix (Bonnefont et al, 2019), to induce a steatosis of the liver. During the development of this hepatic steatosis, several studies have reported differences in the expression levels of genes involved in different cellular pathways such as glycolysis, biosynthesis, transport, storage and oxidation of lipids and cytoskeletal modifications (Zhu et al, 2011; Bax et al, 2012). According to Bax et al (2012), overfeeding can be separated
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