Proteome dataset of subcutaneous adipose tissue from postpartum cows treated with sodium salicylate

Caio Takiya,Shawnee Montgomery,Laman Mamedova,Gitit Kra,Nataly Nemes-Navon,Yishai Levin,Sherry Fleming,Barry Bradford,Maya Zachut

doi:10.1016/j.dib.2019.104567

Caio Takiya, Shawnee Montgomery + Show 7 more

Open Access

https://doi.org/10.1016/j.dib.2019.104567

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Abstract

This article contains raw and processed data related to research published by Takiya et al. [1]. Literature have shown that treatment with the nonsteroidal anti-inflammatory agent sodium salicylate (SS) during the first days postpartum in dairy cows increased lactation performance [2], and tended to alter glucose metabolism [3]. Yet, the specific effects of systemic SS treatment on the proteome of the adipose tissue (AT) and on the inflammatory process in AT of postpartum cows is unknown. Subcutaneous AT samples were collected at 7 d of lactation from control cows (n = 5) and from cows treated with 2.3 g/L SS (n = 5) via drinking water during the first 7 d of lactation. Protein extraction and liquid chromatography-mass spectrometry were performed to obtain proteomics data. Differential abundance of proteins was determined through MS1 intensity based label-free method. Proteomics analysis generated a novel dataset consisted of 1422 proteins, 80 (5.6%) of which were differentially abundant [fold change ± 1.5, P < 0.05 2-way ANOVA] when comparing control and SS-treated cows. The present dataset of subcutaneous AT proteome from postpartum dairy cows treated with SS can be used as a reference for any research involving nonsteroidal anti-inflammatory agent treatment in dairy cows or in comparative research between species.

Highlights

This article contains raw and processed data related to research published by Takiya et al [1]
Literature have shown that treatment with the nonsteroidal anti-inflammatory agent sodium salicylate (SS) during the first days postpartum in dairy cows increased lactation performance [2], and tended to alter glucose metabolism [3]
Biology Physiology Table Liquid Chromatography-Mass spectrometry: nanoAcquity þ Q Exactive Plus Raw Identifications Analyzed Filtered Protein abundance in subcutaneous adipose tissue from the tail-head region of 10 dairy cows Subcutaneous adipose tissue was sampled from the tail-head region of 5 control dairy cows and 5 that were treated daily with sodium salicylate (2.3 g/L) via drinking water

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Biology Physiology Table Liquid Chromatography-Mass spectrometry: nanoAcquity þ Q Exactive Plus Raw Identifications Analyzed Filtered Protein abundance in subcutaneous adipose tissue from the tail-head region of 10 dairy cows Subcutaneous adipose tissue was sampled from the tail-head region of 5 control dairy cows and 5 that were treated daily with sodium salicylate (2.3 g/L) via drinking water. The proteome dataset from subcutaneous AT can be used as a reference for any research involving the use of nonsteroidal anti-inflammatory treatment to postpartum dairy cows. This data can be utilized in pharmacological research interested in the global effects of SS treatment on peripheral tissues in mammals. The dataset of AT proteome may be useful in comparative research between species This data describes the proteome of subcutaneous adipose tissue (AT) from postpartum dairy cows that were either controls or treated with 2.3 g/L of SS in drinking water until 7 d in lactation.

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