Proteinuria Pasien Diabetes Melitus dan Obesitas Poli Penyakit Dalam RS Ibnu Sina Makassar

Abstract

Background: The prevalence of diabetes mellitus in the world has increased which is certainly accompanied by a rapid increase in the incidence of its chronic complications like kidney disorders. Insulin resistance, the patophysiology of diabetes mellitus, also associated with obesity, which both are the main risk factors for cardiovascular events. Obesity also known as a risk factor for kidney disease that proved by the presence of proteinuria in obesity patients. Objective: To determine the correlation of obesity with occurrence of proteinuria in patients with type 2 DM in internal medicine polyclinic Ibnu Sina Hospital Makassar. Method: A cross sectional study on 32 type 2 DM patients at Ibnu Sina Hospital as measured by body weight, height and waist circumference. Urinalysis examination is also performed at that time. Results: In this study, there were 4 patients (12,5%) patients with proteinuria (+), 1 patient (3.1%) with proteinuria (++), 2 patients (6.3%) with proteinuria (+++) and 1 patient (3.1%) with proteinuria (++++). According to BMI, we found that 17 patients (53.1%) were overweight, 5 patients (15.6%) were class 1 obesity, no class 2 obesity patient, and 1 patients (3.1%) were class 3 obesity. In Waist circumference examination we found that in normal waist circumference group there is 1 patient that did not has proteinuria while in the abnormal waist circumference group, 8 patients out of 31 patients have proteinuria. After doing statistical analysis to assess the correlation of obesity with proteinuria obtained p value> 0.05. Similarly, the correlation analysis waist circumference with proteinuria obtained p value> 0.05. Conclusion: There is no correlation between obesity and proteinuria as well as waist circumference and proteinuria correlation in type 2 DM patients.