Proteinuria-associated nutcracker syndrome: an amyloid-negative familial Mediterranean fever patient

Abstract

Sir, Familial Mediterranean fever (FMF) is an autosomal recessive disease, and the most important complication is amyloidosis which leads to end-stage renal disease [1]. Nutcracker syndrome (NCS) is a rare clinical condition manifested by haematuria, proteinuria, gonadal varicose veins and side pain, all due to compression of the left renal vein and renal congestion [2]. Not all the cases of proteinuria in familial Mediterranean fever are due to amyloidosis, and the ‘nutcracker syndrome’ can be one of the confounding causes.