Abstract
Highly synchronized blood infections of Plasmodium chabaudi (strain IP-PCI) were induced in mice. Pulse-labelling in vitro experiments, using [ 35S]methionine, identified 28 proteins whose synthesis is exclusively or preferentially observed during specific stages of the erythrocytic cycle: 11 during the ring stage, 16 from the mature trophozoite and schizont stages and 1 during the schizont stage. An analysis of merozoite proteins that are synthesized at various stages of parasite development indicated that most of the higher molecular weight proteins are synthesized during the schizont stage of the blood cycle.
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