Abstract
Topology and post-translational modifications (PTMs) are critical features in studying the structures and functions of proteins. Several popular and detailed protein visualization algorithms are available for such studies, such as PyMOL, NCBI's iCn3D, UniProt PTM viewing, and Protter. However, none of the studies depict the special relationships between key structural features such as N-glycosylation, disulfide bonds, potential N-glycosylation sites (free sequons), potential disulfide bonds (free cysteine sites), and protein topology in a way conducive to detailed analyses. We introduce Protein Visualizer 2.0 (https://sfu-sun-lab.github.io/protein-visualizer-2.0/), a web-based tool that visualizes these features and the topology of all human proteins. This tool allows users to readily assess potential conflicts among predicted protein topology and known co/post-translational modifications. This tool also helps to reveal hidden relationships among displayed structural features.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
