Abstract

The purpose of this review was to determine whether past research provides conclusive evidence about the effects of type and timing of ingestion of specific sources of protein by those engaged in resistance weight training. Two essential, nutrition-related, tenets need to be followed by weightlifters to maximize muscle hypertrophy: the consumption of 1.2-2.0 g protein.kg -1 of body weight, and ≥44-50 kcal.kg-1 of body weight. Researchers have tested the effects of timing of protein supplement ingestion on various physical changes in weightlifters. In general, protein supplementation pre- and post-workout increases physical performance, training session recovery, lean body mass, muscle hypertrophy, and strength. Specific gains, differ however based on protein type and amounts. Studies on timing of consumption of milk have indicated that fat-free milk post-workout was effective in promoting increases in lean body mass, strength, muscle hypertrophy and decreases in body fat. The leucine content of a protein source has an impact on protein synthesis, and affects muscle hypertrophy. Consumption of 3–4 g of leucine is needed to promote maximum protein synthesis. An ideal supplement following resistance exercise should contain whey protein that provides at least 3 g of leucine per serving. A combination of a fast-acting carbohydrate source such as maltodextrin or glucose should be consumed with the protein source, as leucine cannot modulate protein synthesis as effectively without the presence of insulin. Such a supplement post-workout would be most effective in increasing muscle protein synthesis, resulting in greater muscle hypertrophy and strength. In contrast, the consumption of essential amino acids and dextrose appears to be most effective at evoking protein synthesis prior to rather than following resistance exercise. To further enhance muscle hypertrophy and strength, a resistance weight- training program of at least 10–12 weeks with compound movements for both upper and lower body exercises should be followed.

Highlights

  • The purpose of this review was to determine whether past research provides conclusive evidence about the effects of type and timing of ingesting specific protein sources by those engaged in resistance weight training

  • Leucine and muscle protein synthesis The leucine content of a protein source has an impact on protein synthesis, and affects muscle hypertrophy [10,11,12,13,14,15]

  • After successful engagement of the Pre-initiation complex (43S) pre-initiation complex to RNA, the molecule eukaryotic initiation factor 5 removes eukaryotic initiation factor 2 (eIF2) while a molecule of guanosine triphospahte (GTP) is hydrolyzed so that eIF2 is recycled to its active form of eIF2-GTP [16]

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Summary

Conclusions

Researchers have tested the effects of types and timing of protein supplement ingestion on various physical changes in weightlifters. After about three hours postprandial, MPS drops back to baseline even though serum amino acid levels remain elevated [14] These data show that there is a limited time window within which to induce protein synthesis before a refractory period begins. A combination of a fast-acting carbohydrate source such as maltodextrin or glucose should be consumed with the protein source, as leucine cannot modulate protein synthesis as effectively without the presence of insulin [27,28] and studies using protein sources with a carbohydrate source tended to increase LBM more than did a protein source alone [33,37,38,39,40,41] Such a supplement would be ideal for increasing muscle protein synthesis, resulting in increased muscle hypertrophy and strength.

Lemon P
Findings
16. Stipanuk M
Full Text
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