Abstract
Whole blood, plasma and packed red cell spin-lattice relaxation time data for 50 human and eight fish samples at 20 MHz, and for 35 human samples at 4 MHz are presented. Calculations based on the fast and intermediate exchange limits of the theory of chemical exchange show no noticeable difference in agreement with the experimental data, indicating that the intermediate exchange limit does not give any better agreement than the fast exchange limit. The two-phase model of chemical exchange, while it may be a gross oversimplification of the real state of affairs, does apply at least as a first approximation to the behavior of water protons in blood. The major contributor to the relaxation rate in erythrocytes is hemoglobin. Fish data show no significant difference from human blood data.
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