Abstract

Protein-losing gastroenteropathies are characterized by an excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinemia (detected as hypoalbuminemia), edema, and, in some cases, pleural and pericardial effusions. Protein-losing gastroenteropathies can be caused by a diverse group of disorders and should be suspected in a patient with hypoproteinemia in whom other causes, such as malnutrition, proteinuria, and impaired liver protein synthesis, have been excluded. In this paper, we present a case of protein-losing enteropathy in a 22-year-old immunocompetent male with a coinfection of CMV and Hp.

Highlights

  • Protein-losing gastroenteropathies can be caused by a diverse group of disorders, in which an increase in intestinal leakage of plasma proteins occurs

  • A variety of benign and malignant conditions can be associated with protein-losing gastroenteropathy, for example, Inflammatory bowel disease (IBD) and gastrointestinal malignancies

  • We describe a case of erosive gastritis with significant protein-loss, admitted to our department for evaluation because of vomiting and abdominal pain

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Summary

Introduction

Protein-losing gastroenteropathies can be caused by a diverse group of disorders, in which an increase in intestinal leakage of plasma proteins occurs. This leakage can occur via either mucosal injury or increased lymphatic pressure in the gut. A gastric biopsy in a few reported cases demonstrated the presence of CMV [1, 2]. Most of these patients were children who had a typical benign and transient course and required only supportive therapy [3]. Gastricmucosal biopsy revealed morphological evidence of both CMV and Hp infection

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