Abstract
Protein-DNA interactions play a key role in many fundamental biological processes, such as DNA replication, transcription, and recombination. Very often, the DNA-binding proteins induce structural changes of the target DNA-binding sequences. These DNA structural changes include DNA bending, twisting, and wrapping. Although protein-induced DNA-bending has been widely studied, other protein-induced DNA structural changes have not been fully explored due to the lack of a feasible experimental approach.
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