Protein‐induced B‐Z Transition is Kinetically Accelerated by Introducing Single‐Stranded Regions

Abstract

The presence of single-stranded regions leads to faster B-Z transition possibly by lowering the activation energy. Figure S1. Sequences and schematic structures of representative 5′- or 3′-overhang duplexes and stem-loops used in this study. Unpaired single-stranded regions, overhangs and loops, are written in red. Figure S2. B-Z transition of various 5′-dT-overhang ZFD substrates induced by hZαADAR1. CD spectra of reactions with different DNA substrates, ZFD and T1~T6-ZFDs, at 25°C were obtained before adding hZαADAR1 (in black) and in the presence of hZαADAR1 (in red) after 30 min incubation. Table S1. Oligonucleotides used in this study Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.