Abstract

As a followup to last month`s column on nucleic acid databases, we now turn our attention to the world of proteins. The resources we list in the accompanying table include databases where you can search for specific protein sequences, find two-dimensional protein gel data, or align protein structures. We also found sites where you can predict protein secondary structures or visualize proteins in three dimensions. Touring these sites is an excellent way to observe a new trend that we have observed over the last several months: Customized internet-based software tools are emerging to address highly specific laboratory needs. One of the most rapidly developing categories of these internet-based laboratory tools is the ability to view and rotate protein structures on your local computer. As little as a few months ago, this ability was reserved for those privileged researchers who had dedicated molecular modeling workstations. We look forward to reporting on more of these novel internet-based tools for the laboratory in the near future.

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