Abstract

Abstract A wide range of biomolecules, including proteins, adsorb to nanoparticles when they contact biological fluids. The layer of protein that forms on the nanoparticle surface is called the “protein corona,” which plays a major role in interacting with biological systems. Specifically, the interactions are contingent on the surface properties of coated nanoparticles, such as the identity and amount of bound proteins. In this chapter, we review the composition and interactions of protein coronas based on recent studies. We also discuss their implications with respect to biological fate, therapeutic efficiency, and toxicity, along with their opportunities and challenges in this important area of nanoparticle research.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.