Abstract
The protein level reached maximum concentration in regenerative tissue after 4 days, and then decreased to approximately 1/4 of the maximum by the 28th day. The calcium level rapidly increased between the fourth and seventh days after drilling, maintaining a linear increase throughout the 28-day experimental period. Acid phosphatase activity was at its highest level in regenerative tissue approximately 2 weeks old. The regenerative tissues 4–14 days old actively reorganized the components by degrading the proteins accompanied by calcium accumulation.
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