Abstract
In order to fabricate a soluble conducting polypyrrole matrix, applied as a biomaterial to anchor proteins, the preparation of a poly(acryoyl pyrrole)-g-polypyrrole (PAP-g-PPy) copolymer and the adsorption of bovine serum albumin (BSA) onto this conducting copolymer were studied. Polypyrrole (PPy) was synthesized by electrochemical polymerization on an Au surface, which had been spin-coated with a poly(acryloyl chloride) precursor containing a pyrrole moiety in its side chain. The chemical properties of PPy depend on the polymerization conditions, i.e., the concentration of pyrrole and the polymerization time. Subsequently, the adsorption behavior of BSA on PAP-g-PPy was investigated by surface plasmon resonance spectroscopy, suggesting that the copolymer thickness, the concentration of pyrrole monomer used in the preparation of the polymer, the BSA concentration and the pH value of buffer solutions can affect the adsorption behavior of BSA onto the polymer surface. It is therefore predicted that the conducting copolymer PAP-g-PPy could be used as an adsorbed matrix for protein adsorption.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
