Abstract
A systematic study of the effects of polymer surface properties on the interaction with human endothelial cells (HEC) may lead to the development of improved small-diameter vascular grafts. HEC, suspended in culture medium containing 20% human serum adhere and spread on moderately water-wettable polymers (contact angle of about 40 degrees, Ref. 1). Examples of such polymers are: tissue culture polystyrene (TCPS), tissue culture poly(ethylene terephthalate) (TCPETP), cellulose-3-acetate, and a copolymer of hydroxy-ethyl methacrylate (HEMA) and methyl methacrylate (MMA), mol ratio 25 HEMA/75 MMA.
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