Abstract

The objective of this review is to study the ameliorative effects of natural dietary antioxidants in the maintenance of health and the prevention and treatment of various pathophysiological disorders, with a focus on data pertaining to L-Ascorbic acid or vitamin C and α- Tocopherol or vitamin E. The current study discusses natural and synthetic antioxidants, its mechanism of action as free radical scavengers, protective role in prevention of some major diseases including lifestyle exposure diseases. There appear to be significant health benefits from dietary antioxidants, have important roles in preventing pathogenic processes related to Diabetic neuropathy, major depressive disorder, inflammation, cataract, age-related muscular degeneration, liver disorders, cardiovascular and neurological disorders, asthma and may enhance immune function. The combined supplementation of vitamins were found to be more beneficial in protection against oxidative stress due to their synergistic effects particularly vitamin C and vitamin E. Thus the findings in the present review will throw considerable light on the use of natural dietary antioxidants against various diseases thus adding more information on therapeutic approaches.

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