Abstract
Imidacloprid is a neonicotinoid group insecticide and is widely used in veterinary medicine for the control of pests such as lice and fleas in domestic animals. Insecticides are known that they induce toxic effects on living organism, causing oxidative stress and DNA damage. Taurine plays a role in many physiological and biochemical functions and provides an antioxidant effect by stabilization of biological membranes. This study investigated the effect of imidacloprid on DNA damage and reproductive performance and the possible protective effect of taurine in Drosophila melanogasters. Imidacloprid (0.6 µM) alone or in combination with taurine (1, 2 ve 3 mM) were given to broths for 20 days. The results of the study showed that imidacloprid application decreased reproductive performance and increased DNA damage in groups, whereas these effects decreased with taurine administration. In conclusion, it was determined that the adverse effects of imidacloprid regarding DNA and reproductive performance in Drosophila melanogasters were prevented by taurine application.
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