Abstract
Aflatoxin B1 (AFB1), commonly found in feed stuffs causes hepatocellular carcinoma and immunosuppression. Selenium (Se) is mainly known as an important antioxidant and immunostimulant. To evaluate the protective effects of dietary sodium selenite against AFB1_induced erythocytic toxicology, one hundred male Avian broilers were randomly divided into five groups viz. : fed with basal diet (control group), 0.3mg/kg AFB1 (AFB1 group), 0.3mg/kg AFB1+0.2mg/kg Se (+Se group ‘!), 0.3mg/kg AFB1+0.4mg/kg Se (+Se group a!) and 0.3mg/kg AFB1+0.6mg/kg Se (+Se group b!), respectively. At 7, 14 and 21 days of the experiment, the red blood cells (RBC count), content of hemoglobin (Hb) and the immune adherence function were determined. Compared with control group, the number of RBC in AFB1 group was increased, while the content of Hb and erythrocyte rosette rates in AFB1 group were decreased significantly. Dietary sodium selenite, however, could decrease the number of RBC; increase the content of Hb and erythrocyte rosette rate significantly. It was indicated that sodium selenite in the diets could exert protective effects against AFB1-induced damage on the red blood cells, and the transport capacity and immune adherence function of erythocyte could be maintained.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
