Abstract
Effects of glucocorticoids on gland stiffness and cell coupling in salivary gland cells of Chironomus plumosus were studied by mechanical and electrophysiological measuring. Protective effects of glucocorticoids were observed both on gland stiffness and on cell coupling for procaine, chlorpromazine, EGTA, lipase, trypsin and TEA (tetra-ethylammonium), but not for alcohols, butyric acid and changes in pH of the medium. From these results, it was suggested that the cell system would be protected mechanically and electrically from junctional uncoupling by interaction between glucocorticoids and uncoupling agents at the cell membrane.
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