Abstract
The present study investigates the effect of cyclohexylmethyldithiocarbamates sodium salt (a synthetic compound) and vitamin E against diclofenac-induced blood and testes of experimental Wistar male albino rats. The study consists of six groups of six rats each. Group I (control) received corn oil (3 ml/kg b.w), Group II received diclofenac (100 mg/kg b.w), Group III rats were treated with diclofenac and cyclohexylmethyldithiocarbamates sodium salt (30 mg/kg b.w), Group IV was administered diclofenac and Vitamin E (30 mg/kg b.w), Group V was given cyclohexylmethyldithiocarbamates sodium salt (30 mg/kg b.w) only and Group VI received vitamin E only. The results showed a significant (p 0.05) in the vitamin E only treated rats when compared with the control. There was a significant (p 0.05) decrease in the diclofenac with Na (HxMedtc) treated rats and Na (HxMedtc) only treated rats when compared with the control. Also, there was a significant (p<0.05) decrease in TSN in the diclofenac with Na (HxMedtc) treated rats and diclofenac with vitamin E treated rats when compared with diclofenac only treated rats. And a decrease (p<0.05) in the daily sperm production (DSP) in the diclofenac only treated rats, and diclofenac with cyclohexylmethyldithiocarbamate sodium salt only treated rats when compared with the control.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
