Abstract
ABSTRACT The present day medical management of calculi is either costly or not without side effects. Hence, the search of anticalculi drugs from natural sources has been assumed greater importance. Chives (Allium schoenoprasum, L.) is a long-lived plant which is very easy to grow. It contained a variety of phytochemical compounds and various minerals. This aim of this research was to evaluate exposed of anticalculi activity of fresh and dried chives leaves infuse on male albino Wistar rats using 0.75 % ethylene glycol and 2 % ammonium chloride induction method. Animals in treatment group are given 10 % of fresh and dried chives leaves infuse. Anticalculi activity in the chives leaves infuse examined by observing the kidney weight ratio, calcium level in kidney, urinary calcium level, urinary oxalate level, and creatinine serum level. From the data obtained, there were significant differences in treated group from negative control group. The biggest effect of dissolving the calcium oxalate crystal in kidney was the dried chives leaves infuse. Based on the above results, it could be concluded that chives leaves could be an alternative to calculi disease treatment.
Highlights
Kidney stone or calculi disease has become a rising problem and the third relevant disorder affecting the urinary tract with high recurrence
Chives (Allium schoenoprasum, L.) is a long-lived plant which is very easy to grow. It contained a variety of phytochemical compounds and various minerals. This aim of this research was to evaluate exposed of anti-calculi activity of fresh and dried chives leaves infuse on male albino Wistar rats using 0.75 % ethylene glycol and 2 % ammonium chloride induction method
Anticalculi activity in the chives leaves infuse examined by observing the kidney weight ratio, calcium level in kidney, urinary calcium level, urinary oxalate level, and creatinine serum level
Summary
Kidney stone or calculi disease has become a rising problem and the third relevant disorder affecting the urinary tract with high recurrence. The search of anti-calculi drugs from natural sources has assumed greater importance (Amin, et al, 2015). Herbal drugs are the oldest sources for the preventing, medication, treatment and even diagnostic tools know to mankind. Chives can be used to treat many diseases such as vaginal discharge, constipation and infectious germs in the intestines, speed up the blood flow, prevent blood clotting, antioxidants, breast cancer, antiinflammatory and antihypertensive (Andarwulan and Faradilla, 2012; Amalia, et al, 2008; Jalkumar and Jasmine, 2016; Parvu, et al, 2014; Sachinm, et al, 2010)
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