Abstract
Purpose: To examine the effect of Sempervivum tectorum aqueous extract , as infusion, on some biomarkers of oxidative stress induced by aluminium exposure in Wistar albino rat. Methods: The rats were randomly divided into five groups and treated daily for 3 months as follows: control received tap water; the 2 nd group was given 1 mg/L aluminium as aluminium sulphate (AS) in drinking water daily; group 3, a combination of 1 mg/L AS and Sempervivum tectorum extract daily; the fourth group, Sempervivum tectorum extract daily; and fifth group 1 mg/L AS for three months and thereafter Sempervivum tectorum extract for one month. Results: Aluminium (Al) exposure increased, compared to control group, the level of blood Al (293.64 %, p 0.05), glutathione peroxidase (G-Px, 31.25 %, p 0.05) affected by the extract. Conclusion: S. tectorum extract possesses antioxidant activity against free radicals produced in blood as a result of aluminium exposure.
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