Abstract
Thermal burn injuries are still a serious public health concern. Severe burns cause both local skin and distant-organ injuries. Many pathological mechanisms are involved in burn-induced injuries. Overproduction of reactive oxygen species (ROS) and oxidative stress play key roles in the pathogenesis of the systemic response and serious complications after burns. Antioxidants are intensively studied, and their beneficial effects are documented. Regardless of that, they still attract the researchers' interest in uncovering new evidence about their favorable impact on burn injuries. This review aims to describe recent evidence related to the mechanisms of tissue protection after administering some antioxidants with biogenic origins in burns.
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