Abstract
The effect of the carbamate insecticide “carbofuran” on testes of male albino mice and the possible protective role of vitamin C against the insecticide toxicity was assessed. Treating mice with carbofuran for 8 weeks induced a significant decrease in the diameters and germinal epithelial heights of the seminiferous tubules. The histological evidence showed inhibition of spermatogenesis. There was also a decline in sperm count. Histochemical results revealed that animals given carofuran had decreased contents of carbohydrates and total proteins in the testicular tissue. Treating mice with carbofuran and vitamin C showed an improvement in the testicular damage. The seminiferous tubules appeared normal and the different stages of spermatogenic cells showed an advanced degree of activation. The present work is supported by Umm Al‐Qura University
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